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CBDPure Hemp Oil 600 (#1 Best Overall CBD Oil for Pain) cbdpureCBD Pures Hemp Oil 600 takes the #1 spot, and for good reason. No other brand came close in potency and speed in managing our pain symptoms. CBDPure oils are made from domestic Colorado-grown organic hemp. Unlike most other CBD oil brands that we put to the test, CBDPures oil contains full spectrum cannabinoids and terpenes, enhancing the oils therapeutic effect. Their hemp oil is 100% free of synthetic and artificial ingredients, and every batch is tested for potency and quality by third-party labs. Noteworthy features: Legal in all 50 states (unlike marijuana-based CBD oil vendors) Full-spectrum cannabinoids and terpenes Sourced from cold press CO2 extraction Tested by independent 3rd party labs for purity 90-day 100% money back guarantee Our take on CBD Pure Hemp Oil: CBDPures has earned a well-deserved reputation as the go-to CBD oil choice among chronic pain sufferers. 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These, however, are only just a few examples of what the Koi CBD oil has done for patients. Some CBD users even claim that the product has helped them with the restless leg syndrome, while others stopped experiencing problems with memory loss. Price: $39.00 $249.00 CBD Oil: Your Natural Painkiller Thankfully, over the last couple of years, CBD oil has become extremely popular for treating pain-related issues. It can be found both online as well as local health stores. Actually, cannabidiol has proven so effective that more and more medical professionals are choosing it instead of traditional painkillers as the go-to treatment. The reason why scientists have become so CBD-optimistic these days lies in the very nature of cannabidiol. This natural chemical compound of cannabis interacts with the endocannabinoid system in our bodies, and therefore, helps them regulate a wide range of vital processes. Most importantly, CBD is non-intoxicating, meaning that it wont take you high unlike THC, its psychoactive brother. In addition to being a trusted source of pain relief, CBD has been proven by numerous studies to promote anti-anxiety effects and induce what the users commonly refer to as tranquility and full alertness. Finally, cannabidiol does not interact with the brains reward area, so in other words, its non-addictive. The majority of science-backed evidence supporting the benefits of using CBD oil for pain comes from animal studies and preclinical human research, which is one of the major reasons why cannabidiol remains unapproved by FDA. Nonetheless, as the legal status of CBD is continuously heading towards the bright future, there is hope that we will soon be able to see more in-depth studies emerging from the scientific world. Plus, let us not forget that there are massive numbers of self-reports coming from patients using CBD as their go-to painkiller, so even in the light of relatively modest data about cannabidiol, we cant deny that there has to be something about it. Theres no other way than to experience the potential therapeutic effects of CBD first hand. But before we move on to our list of 10 best CBD oils for pain, lets shed light on the analgesic mechanism of this cannabinoid. CBD Oil For Pain: Cannabidiol And the Endocannabinoid System People have been using cannabis for a plethora of reasons. The earliest records of the medical use of the plant date back to ancient China, when the emperor Shen-Nung used cannabis for the first time and encouraged his advisors to place the plant among other therapeutic substances in the Chinese encyclopedia of medicine. The people of India, on the other hand, have been using cannabis as a mixture of the plant and milk; the mix is known as bhang. To cut the long story short, cannabis has long been a known medicine, but only recently scientists have managed to answer the question that bothered them most: why? Since the discovery of the endocannabinoid system, followed by the cannabis revolution in the U.S. over the last decade, CBD and other phytocannabinoids have gained much of the spotlight in the world of contemporary medicine. Just as we mentioned before, the endocannabinoid system is responsible for maintaining homeostasis in the body by regulating a variety of vital processes; these include: Appetite control Pain-sensation Memory Mood Stress management Maintaining chemical balance in the gut The endocannabinoid system produces something we call endocannabinoids our inner cannabis. These endocannabinoids are released to regulate the above processes whenever things get out of controls. Then, those endocannabinoids tap to two different kinds of receptors: CB1 and CB2 receptors. CB2 receptors are mostly associated with THC, the intoxicating agent in cannabis, and the interaction between these two explains why we get high. CB1 receptor, on the other hand, interacts with CBD, which is where all the magic happens. Lets take a look at the current research on the use of CBD oil for pain. How Does CBD Oil Relieve Pain? Like we said, dealing with pain is about more than taking a magical pill and waiting for the effects to come. If you really want to alleviate your health concerns, you need to get to the roots of the problem, which is what CBD does best. To answer the question, CBD relieves pain by: Reducing inflammation Providing immunomodulatory effects Acting as a neuroprotectant and antioxidant. The exact way in which CBD oil works for pain relief is still being studied around the world. Yet, what we do know thus far is, least to say, promising. Using CBD Oil for Chronic Pain At the very beginning of the article, weve mentioned a word about CBD being tested on animal models to prove its analgesic properties. As it has been demonstrated repeatedly in animal studies the majority of them was performed on rats that cannabidiol in its oil form can be useful for treating all forms of pain. Even though more clinical trials on humans are needed to determine how CBD affects specific diseases, scientists believe that the success of CBD oil for treating chronic pain is related to the anti-inflammatory properties of the cannabinoid. CBD Oil and Arthritis Preclinical studies suggest that CBD oil can be one of the most effective choices for arthritis and other forms of localized pain caused by inflammation. Researchers have found a clear link between the endocannabinoid system and the pathophysiology of osteoarthritis, which is a degenerative joint disease associated with inflammation. CBD stimulates the work of CB1 receptors, helping them bring the chemical balance in the immune system, reduce inflammation, and relieve pain as a result. Can CBD Oil Help With Multiple Sclerosis? According to the preclinical animal evidence yes, it can. Since CBD works as a neuroprotectant because of its antioxidant and anti-inflammatory properties, it can be an effective form of treatment for multiple sclerosis, which afflicts 50-70% patients with a debilitating pain. The animal study at Cajal Institute aimed at finding out if CBD provides reversed inflammatory responses on cell cultures; it took only 10 days for the mice to show improved pain management, superior motor skills, and general progression in their illness. However, theres plenty of other research papers suggesting that CBD has powerful analgesic properties. Actually, there have been over 20,000 scientific studies on cannabinoids and their therapeutic effects on different sorts of health concerns. CBD Oil in Sports: Injuries & Muscle Endurance Cannabidiol can be applied in two different ways when it comes to pain and physical activities. For example, when you administer CBD orally in the form of oil as a post-workout, it helps alleviate the muscle inflammation that troubles athletes once they go beyond the edge again. If, however, youre suffering from an injury, its best to apply CBD topically. Its anti-inflammatory and neuroprotective properties allow the cannabinoid to relieve pain and improve regeneration capacities. Are There Any Side Effects of CBD Oil? The main reason why people are so crazy about CBD is that this cannabinoid is non-intoxicating and doesnt come with any severe side effects. According to the scientific research, when applied in doses up to over a gram and one-half have no side effects on health whatsoever. This makes CBD completely safe for both adults and children; more interestingly, some CBD companies offer pet care products in their assortment, because cannabidiol is safe for animals as well. Last but not least, CBD doesnt show any of the side effects associated with the use of conventional painkillers, such as heart attacks, addiction, strokes, ulcers, and liver failures. That being said, you can use CBD oil for pain on a daily basis with no risk to your health. CBD Oil For Pain: A New Hope Thankfully, gone are the times when doctors were prescribing traditional painkillers and anti-inflammatories like candies. Now, with a greater level of awareness in terms of the complexity of chronic issues such as pain, for example we know that there is no magic pill to solve the issue and we need to defeat the core of the problem in order to get back on track with our lives. In the light of the growing body of both scientific and anecdotal evidence, there is much hope in CBD for the future treatment of chronic pain, inflammation, and neurodegenerative issues. Cannabidiol succeeds where pharmaceuticals fail, which is why it has managed to conquer the hearts of patients from all over the world. CBD is non-intoxicating, it comes with a plethora of potential therapeutic benefits, and above all, it has no side effects of traditional painkillers. That being said, you can use it both acutely and as a regular supplement to combat your health conditions on a long-term basis. All in all, we cannot help but hope there will be more in-depth research into the relationship between CBD and pain management. Only then will cannabidiol become a globally acknowledged medicine. 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Charlottes Web Hemp Extract If you know the story of Charlotte Figi, a girl who suffered from Dravet syndrome and was experiencing a great number of seizure attacks until she was given one magical, CBD-rich strain bred by Stanley Brothers. As you may have already noticed, the strain was named after the girl. Noteworthy features: Sourced from the worlds famous high-CBD strain, Charlottes Web Full spectrum of cannabinoids, amino acids, and terpenes Offers high potency, Contains only the highest-quality hemp oil, Lab tested for purity Our take on Charlottes Web Hemp Extract: Their famous strain has been transformed into a plethora of products, including their top-shelf CBD oil. This is a whole plant extract, meaning that it also contains other cannabinoids including CBG, CBN, and CBC as well as amino acids, phytonutrients, and terpenes. Price: $39.99 299.96 9. CBD Pain Cream Okay, this is not a CBD oil, but its so effective that it very well deserves the 6th place on our list. This product has conquered the hearts of medical patients and athletes thanks to its effectiveness in relieving pain and reducing inflammation. Noteworthy features: 100% organic No artificial additives Super effective in relieving pain and fighting inflammation Comes at competitive prices Can be applied topically Our take on CBD Pain Cream: The product is truly revolutionary; even top chiropractic offices and holistic retailers use it to help people fight with pains, aches, arthritis, and sports injuries. Most importantly, you can draw from all those benefits for only $40, which is pretty amazing if you ask us. Last but not least, using the CBD pain cream is easy like a walk in a park. All you need to do is to apply a small amount of the cream to any injured or aching area and rub it in so that it gets absorbed by your skin. Use it every 4 to 6 hours and you will be astonished by the results. Price: $40.00 10. Koi CBD Isolate (0 % THC) If youre looking for a CBD oil that has full traceability from the very sourcing to the finished product, Koi CBD will live up to your standards. The company offers one of the cleanest oils on the market, one that is THC-free involves no use of hexane and any harsh solvents, and contains no GMO. Noteworthy features: Sourced from 100% organic hemp Free of GMO, pesticides, and chemical fertilizers 0% THC Perfect for pain and anxiety Lab tested In addition to their outstanding transparency, Koi CBD offers a wide selection of products; the list includes CBD oils, vape liquids, pet treats, CBD topicals, and edibles. We have searched the Internet for user reviews and weve managed to find several common denominators for each case. In other words, each of the examined customers reported strong pain relief, reduced anxiety, improved stress management, better appetite control, and a clear mind. These, however, are only just a few examples of what the Koi CBD oil has done for patients. Some CBD users even claim that the product has helped them with the restless leg syndrome, while others stopped experiencing problems with memory loss. Price: $39.00 $249.00 CBD Oil: Your Natural Painkiller Thankfully, over the last couple of years, CBD oil has become extremely popular for treating pain-related issues. It can be found both online as well as local health stores. Actually, cannabidiol has proven so effective that more and more medical professionals are choosing it instead of traditional painkillers as the go-to treatment. The reason why scientists have become so CBD-optimistic these days lies in the very nature of cannabidiol. This natural chemical compound of cannabis interacts with the endocannabinoid system in our bodies, and therefore, helps them regulate a wide range of vital processes. Most importantly, CBD is non-intoxicating, meaning that it wont take you high unlike THC, its psychoactive brother. In addition to being a trusted source of pain relief, CBD has been proven by numerous studies to promote anti-anxiety effects and induce what the users commonly refer to as tranquility and full alertness. Finally, cannabidiol does not interact with the brains reward area, so in other words, its non-addictive. The majority of science-backed evidence supporting the benefits of using CBD oil for pain comes from animal studies and preclinical human research, which is one of the major reasons why cannabidiol remains unapproved by FDA. Nonetheless, as the legal status of CBD is continuously heading towards the bright future, there is hope that we will soon be able to see more in-depth studies emerging from the scientific world. Plus, let us not forget that there are massive numbers of self-reports coming from patients using CBD as their go-to painkiller, so even in the light of relatively modest data about cannabidiol, we cant deny that there has to be something about it. Theres no other way than to experience the potential therapeutic effects of CBD first hand. But before we move on to our list of 10 best CBD oils for pain, lets shed light on the analgesic mechanism of this cannabinoid. CBD Oil For Pain: Cannabidiol And the Endocannabinoid System People have been using cannabis for a plethora of reasons. The earliest records of the medical use of the plant date back to ancient China, when the emperor Shen-Nung used cannabis for the first time and encouraged his advisors to place the plant among other therapeutic substances in the Chinese encyclopedia of medicine. The people of India, on the other hand, have been using cannabis as a mixture of the plant and milk; the mix is known as bhang. To cut the long story short, cannabis has long been a known medicine, but only recently scientists have managed to answer the question that bothered them most: why? Since the discovery of the endocannabinoid system, followed by the cannabis revolution in the U.S. over the last decade, CBD and other phytocannabinoids have gained much of the spotlight in the world of contemporary medicine. Just as we mentioned before, the endocannabinoid system is responsible for maintaining homeostasis in the body by regulating a variety of vital processes; these include: Appetite control Pain-sensation Memory Mood Stress management Maintaining chemical balance in the gut The endocannabinoid system produces something we call endocannabinoids our inner cannabis. These endocannabinoids are released to regulate the above processes whenever things get out of controls. Then, those endocannabinoids tap to two different kinds of receptors: CB1 and CB2 receptors. CB2 receptors are mostly associated with THC, the intoxicating agent in cannabis, and the interaction between these two explains why we get high. CB1 receptor, on the other hand, interacts with CBD, which is where all the magic happens. Lets take a look at the current research on the use of CBD oil for pain. How Does CBD Oil Relieve Pain? Like we said, dealing with pain is about more than taking a magical pill and waiting for the effects to come. If you really want to alleviate your health concerns, you need to get to the roots of the problem, which is what CBD does best. To answer the question, CBD relieves pain by: Reducing inflammation Providing immunomodulatory effects Acting as a neuroprotectant and antioxidant. The exact way in which CBD oil works for pain relief is still being studied around the world. Yet, what we do know thus far is, least to say, promising. Using CBD Oil for Chronic Pain At the very beginning of the article, weve mentioned a word about CBD being tested on animal models to prove its analgesic properties. As it has been demonstrated repeatedly in animal studies the majority of them was performed on rats that cannabidiol in its oil form can be useful for treating all forms of pain. Even though more clinical trials on humans are needed to determine how CBD affects specific diseases, scientists believe that the success of CBD oil for treating chronic pain is related to the anti-inflammatory properties of the cannabinoid. CBD Oil and Arthritis Preclinical studies suggest that CBD oil can be one of the most effective choices for arthritis and other forms of localized pain caused by inflammation. Researchers have found a clear link between the endocannabinoid system and the pathophysiology of osteoarthritis, which is a degenerative joint disease associated with inflammation. CBD stimulates the work of CB1 receptors, helping them bring the chemical balance in the immune system, reduce inflammation, and relieve pain as a result. Can CBD Oil Help With Multiple Sclerosis? According to the preclinical animal evidence yes, it can. Since CBD works as a neuroprotectant because of its antioxidant and anti-inflammatory properties, it can be an effective form of treatment for multiple sclerosis, which afflicts 50-70% patients with a debilitating pain. The animal study at Cajal Institute aimed at finding out if CBD provides reversed inflammatory responses on cell cultures; it took only 10 days for the mice to show improved pain management, superior motor skills, and general progression in their illness. However, theres plenty of other research papers suggesting that CBD has powerful analgesic properties. Actually, there have been over 20,000 scientific studies on cannabinoids and their therapeutic effects on different sorts of health concerns. CBD Oil in Sports: Injuries & Muscle Endurance Cannabidiol can be applied in two different ways when it comes to pain and physical activities. For example, when you administer CBD orally in the form of oil as a post-workout, it helps alleviate the muscle inflammation that troubles athletes once they go beyond the edge again. If, however, youre suffering from an injury, its best to apply CBD topically. Its anti-inflammatory and neuroprotective properties allow the cannabinoid to relieve pain and improve regeneration capacities. Are There Any Side Effects of CBD Oil? The main reason why people are so crazy about CBD is that this cannabinoid is non-intoxicating and doesnt come with any severe side effects. According to the scientific research, when applied in doses up to over a gram and one-half have no side effects on health whatsoever. This makes CBD completely safe for both adults and children; more interestingly, some CBD companies offer pet care products in their assortment, because cannabidiol is safe for animals as well. Last but not least, CBD doesnt show any of the side effects associated with the use of conventional painkillers, such as heart attacks, addiction, strokes, ulcers, and liver failures. That being said, you can use CBD oil for pain on a daily basis with no risk to your health. CBD Oil For Pain: A New Hope Thankfully, gone are the times when doctors were prescribing traditional painkillers and anti-inflammatories like candies. Now, with a greater level of awareness in terms of the complexity of chronic issues such as pain, for example we know that there is no magic pill to solve the issue and we need to defeat the core of the problem in order to get back on track with our lives. In the light of the growing body of both scientific and anecdotal evidence, there is much hope in CBD for the future treatment of chronic pain, inflammation, and neurodegenerative issues. Cannabidiol succeeds where pharmaceuticals fail, which is why it has managed to conquer the hearts of patients from all over the world. CBD is non-intoxicating, it comes with a plethora of potential therapeutic benefits, and above all, it has no side effects of traditional painkillers. That being said, you can use it both acutely and as a regular supplement to combat your health conditions on a long-term basis. All in all, we cannot help but hope there will be more in-depth research into the relationship between CBD and pain management. Only then will cannabidiol become a globally acknowledged medicine. 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